The Naveni proximity ligation platform pushes the boundries of fluorescence-based in situ methodology, enabling researchers to get the maximum information from every analysis by localizing and quantifying proteins, their interactions and modifications, in situ at the molecular level. Increased sensitivity compared to conventional in situ PLA, enables detection of very low abundant proteins and ensures that proteins can be investigated without the need to over-express, or in any way modify the native environment of the cell.