Assay database

Demonstrated assays and protocols for targeted protein-protein interactions, and specific protein detection

Assay database

Demonstrated assays and protocols for targeted protein-protein interactions, and specific protein detection

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Internal assays

Explore the world of Naveni® in situ proximity ligation technology through our curated collection of assays. Our expert team has meticulously examined each assay, revealing the profound impact our technology has on illuminating protein function in spatial proteomics.

Internal assays

Explore the world of Naveni® in situ proximity ligation technology through our curated collection of assays. Our expert team has meticulously examined each assay, revealing the profound impact our technology has on illuminating protein function in spatial proteomics.

PD1/SHP-2 interaction in diffuse T cell lymphoma, visualized using NaveniBright AP

The importance of PD1/SHP-2 interactions in PD1 signaling

Get more insight into the biological relevant interactions between PD1 and SHP-2, assay protocol available.

Positive HER2 in malignant breast cancer detected with NaveniBright

Precise and specific detection of HER2

See examples of the outstanding detection of HER2 using dual antibody recognition, learn how to use the protocol.

Mesothelin and Mucin interaction in ovary fluorescence readout

Visualize mesothelin and mucin interactions: Insights into cancer dynamics

Read about the importance of mesothelin and mucin interactions in cancer dynamics, and get the assay protocol.

Histon H3 Lamin B1 interaction in MCF7 cells

Explore nucleus and chromatin dynamics: protein-protein interaction histone H3/lamin B1

Witness the cellular saga revealing the dynamic interplay of histone H3 and lamin B1 in key cellular events. Examples and protocol available.

E cadherin Beta catenin interaction healthy colon NaveniFlex Tissue​

E-cadherin/β-catenin interactions and their impact on cell adhesion and cancer

Read about the disruption of E-cadherin/β-catenin interaction and the initiation of cancer progression.

PD1/SHP-2 interaction in diffuse T cell lymphoma, visualized using NaveniBright AP

The importance of PD1/SHP-2 interactions in PD1 signaling

Get more insight into the biological relevant interactions between PD1 and SHP-2, assay protocol available.

Positive HER2 in malignant breast cancer detected with NaveniBright

Precise and specific detection of HER2

See examples of the outstanding detection of HER2 using dual antibody recognition, learn how to use the protocol.

Mesothelin and Mucin interaction in ovary fluorescence readout

Visualize mesothelin and mucin interactions: Insights into cancer dynamics

Read about the importance of mesothelin and mucin interactions in cancer dynamics, and get the assay protocol.

Histon H3 Lamin B1 interaction in MCF7 cells

Explore nucleus and chromatin dynamics: protein-protein interaction histone H3/lamin B1

Witness the cellular saga revealing the dynamic interplay of histone H3 and lamin B1 in key cellular events. Examples and protocol available.

E cadherin Beta catenin interaction healthy colon NaveniFlex Tissue​

E-cadherin/β-catenin interactions and their impact on cell adhesion and cancer

Read about the disruption of E-cadherin/β-catenin interaction and the initiation of cancer progression.

Published assays using Naveni® technology

Our Naveni® technology and Naveni® product lines are frequently referred to in peer-reviewed scientific publications. Below is a summary of assays detected using our Naveni® technology.

Naveni® product line

Protein targets

Sample type

Research Area

Journal

Publication

NaveniFlex MR

S100A4 apelin

Human cell lines

Cardiovascular (atherosclerosis)

Scientific Reports

NaveniFlex MR

CXCR4

LPA1

Human cell lines

Cell signaling

Cell Communication and Signaling

NaveniFlex MR

HTT

KIF1A

Primary neurons

Neuroscience

eLife

NaveniFlex MR

PDHA1

MAP1LC3B

Rat cardiomyoblasts

Autophagy

Autophagy

NaveniFlex MR

p53

amyloid oligomer A11

Human ovarian FFPE cancer tissue

Ovarian cancer

Oncogene

NaveniFlex MR

FLAG-MRGPRX4

HA-RAMP

Human cell lines

Liver disease

Journal of Biological Chemistry

NaveniFlex MR

Arc

Stargazin

Bassoon

mCherry

Free-floating tissue sections

Neuroscience

Frontiers in Molecular Neuroscience

NaveniFlex MR

EGFR

PDGFR-β

Clathrin

Caveolin

Human cell lines

Cell signaling

Biochemical and Biophysical Research Communications

NaveniFlex GR

GALR2

Y1R

Free-floating tissue sections

Neuroscience

Biomedicine & Pharmacotherapy

NaveniFlex MR

SERCA2 ATPase

Perilipin 5

Primary cardiomyocytes

Cardiovascular

Life Science Alliance

NaveniFlex MR

GluA1

GluA2

Shank3

Primary rat neurons

Neuroscience

Neuroscience Letters

NaveniFlex MR

p110ɑ-PI3K

Ras

Human cell lines

Cell signaling

Life Science Alliance

NaveniFlex MR

AR

AR

PRMT5

MMA

SDMA

Human cell lines

Nuclear receptors

Science Advances

NaveniFlex MR

ErbB4

STAT5a

β1 integrin

Human cell lines

RTKs/ Cell signaling

Nature Communications

NaveniFlex MR

ENO1

PCNA

Human cell lines

Metabolism

Oncogene

NaveniFlex GR

SUSD4

EGFR

Human cell lines

Breast cancer

Journal of Experimental & Clinical Cancer Research

NaveniFlex MR

MAP2K7

EEF1AKMT3

Human cell lines

Tumor metastasis

Cancer Letters

NaveniFlex MR

NMNAT2

NMNAT2

Western blot membranes

Neurobiology

Neurobiology of Disease

NaveniFlex MR

HA tag

HA tag

NACA

NACA

EBNA1

Human cell lines

Protein folding

Nucleic Acids Research

NaveniFlex MR

PDGFR-β

GRB2

PI3K

Clathrin

Human cell lines

Cell signaling

Cellular Signaling

Published assays using Naveni® technology

Our Naveni® technology and Naveni® product lines are frequently referred to in peer-reviewed scientific publications. Below is a summary of assays detected using our Naveni® technology.

Naveni® product line

Protein targets

Sample type

Research Area

Journal

Publication

NaveniFlex MR

S100A4 apelin

Human cell lines

Cardiovascular (atherosclerosis)

Scientific Reports

NaveniFlex MR

CXCR4

LPA1

Human cell lines

Cell signaling

Cell Communication and Signaling

NaveniFlex MR

HTT

KIF1A

Primary neurons

Neuroscience

eLife

NaveniFlex MR

PDHA1

MAP1LC3B

Rat cardiomyoblasts

Autophagy

Autophagy

NaveniFlex MR

p53

amyloid oligomer A11

Human ovarian FFPE cancer tissue

Ovarian cancer

Oncogene

NaveniFlex MR

FLAG-MRGPRX4

HA-RAMP

Human cell lines

Liver disease

Journal of Biological Chemistry

NaveniFlex MR

Arc

Stargazin

Bassoon

mCherry

Free-floating tissue sections

Neuroscience

Frontiers in Molecular Neuroscience

NaveniFlex MR

EGFR

PDGFR-β

Clathrin

Caveolin

Human cell lines

Cell signaling

Biochemical and Biophysical Research Communications

NaveniFlex GR

GALR2

Y1R

Free-floating tissue sections

Neuroscience

Biomedicine & Pharmacotherapy

NaveniFlex MR

SERCA2 ATPase

Perilipin 5

Primary cardiomyocytes

Cardiovascular

Life Science Alliance

NaveniFlex MR

GluA1

GluA2

Shank3

Primary rat neurons

Neuroscience

Neuroscience Letters

NaveniFlex MR

p110ɑ-PI3K

Ras

Human cell lines

Cell signaling

Life Science Alliance

NaveniFlex MR

AR

AR

PRMT5

MMA

SDMA

Human cell lines

Nuclear receptors

Science Advances

NaveniFlex MR

ErbB4

STAT5a

β1 integrin

Human cell lines

RTKs/ Cell signaling

Nature Communications

NaveniFlex MR

ENO1

PCNA

Human cell lines

Metabolism

Oncogene

NaveniFlex GR

SUSD4

EGFR

Human cell lines

Breast cancer

Journal of Experimental & Clinical Cancer Research

NaveniFlex MR

MAP2K7

EEF1AKMT3

Human cell lines

Tumor metastasis

Cancer Letters

NaveniFlex MR

NMNAT2

NMNAT2

Western blot membranes

Neurobiology

Neurobiology of Disease

NaveniFlex MR

HA tag

HA tag

NACA

NACA

EBNA1

Human cell lines

Protein folding

Nucleic Acids Research

NaveniFlex MR

PDGFR-β

GRB2

PI3K

Clathrin

Human cell lines

Cell signaling

Cellular Signaling