NaveniFlex

NaveniFlex offers a fluorescence-based in situ method to detect proteins, protein-protein interactions, and modifications of proteins in various types of samples, including cultured cells, fresh-frozen samples, and FFPE samples. Specifically, for tissue samples, we have the optimized kit NaveniFlex Tissue, and for cell samples, the NaveniFlex Cell kit is recommended. These kits are built upon the Naveni® in situ proximity ligation technology, ensuring reliable and accurate results with precise staining that can be quantified. The kits are versatile, accommodating the use of two primary antibodies, and they come with Navenibodies for secondary detection. The choice of kit depends on the primary IgG host species you are working with.

Experience superior precision and efficiency in your research with these advanced kits designed for cell and tissue samples. Transitioning is effortless, with FAQs to assist you, and our dedicated team ready to support your needs. 

Read more about the new kits in the app note (PDF).

NaveniFlex Cell MR Atto647N

NaveniFlex Cell MR Atto647N

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The NaveniFlex Cell MR Atto647N assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with Atto647N fluorophore is included. 
NaveniFlex Cell MR Red protein-protein interaction

NaveniFlex Cell MR Red

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.
NaveniFlex Cell GM Red protein-protein interaction

NaveniFlex Cell GM Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with TEX615 fluorophore is included.
NaveniFlex Cell GR Red protein-protein interaction

NaveniFlex Cell GR Red

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with TEX615 fluorophore is included. 

NaveniFlex Tissue GM Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with Atto647N fluorophore is included. 

NaveniFlex Tissue GM Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with TEX615 fluorophore is included. 

NaveniFlex Tissue GR Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with Atto647N fluorophore is included.
Microscopic image of protein interactions

NaveniFlex Tissue GR Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.
NavenFlex Tissue MR_Atto Colon Beta-Catenin_E-Cadherin interaction

NaveniFlex Tissue MR Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with Atto647N fluorophore is included 

NaveniFlex Tissue MR Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included 
NaveniLink Kit

NaveniLink

Conjugate your own primary antibodies. The NaveniLink kit is for conjugating oligos and primary antibodies for the creation of Navenibodies. The kit is compatible with NaveniFlex Cell, NaveniFlex Tissue and NaveniBright. 
NaveniFlex Cell GM Atto647N

Naveni Control Kit

Control kit to identify positive signals in proximity ligation assays. Use together with NaveniFlex Cell/Tissue/Bright MR.

Naveni® TriFlex Cell

Fluorescence detection of two proteins in a free and complex state. Based on the Naveni® in situ proximity ligation technology, the in situ kit provides accurate data with precise staining of total protein A, total protein B, and the interaction AB between the two proteins. Validated for cell samples.

Naveni TriFlex Cell MR

Detect and quantify total protein A, total protein B, and the interaction AB between the two proteins. The assay is designed to be used with a mouse and rabbit primary antibody pair.

NaveniBright

Chromogenic detection of proteins, protein – protein interactions, or protein modifications in cultured cells as well as in fresh-frozen and FFPE samples. Based on the Naveni® in situ proximity ligation technology, the in situ kits provide accurate data with precise staining and visualization of the full tissue morphology with brightfield. The kit includes Navenibodies for secondary detection to be used with a mouse and rabbit primary antibody pair, choose kit depending on AP or HRP preference.

NaveniBright AP in Ovary

NaveniBright AP

Detect proteins, protein – protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Chromogenic readout with AP substrate.

NaveniBright HRP

Detect proteins, protein – protein interactions, or protein modifications. The assay is designed to be used with a mouse and a rabbit primary pair. Chromogenic readout with HRP substrate.  
NaveniFlex Cell MR Atto647N

NaveniFlex Cell MR Atto647N

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The NaveniFlex Cell MR Atto647N assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with Atto647N fluorophore is included. 
NaveniFlex Cell MR Red protein-protein interaction

NaveniFlex Cell MR Red

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.
NaveniFlex Cell GM Red protein-protein interaction

NaveniFlex Cell GM Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with TEX615 fluorophore is included.
NaveniFlex Cell GR Red protein-protein interaction

NaveniFlex Cell GR Red

Detect proteins, protein-protein interactions, or protein modifications in cell samples. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with TEX615 fluorophore is included. 

NaveniFlex Tissue GM Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with Atto647N fluorophore is included. 

NaveniFlex Tissue GM Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and mouse primary antibody pair. Detection with TEX615 fluorophore is included. 

NaveniFlex Tissue GR Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with Atto647N fluorophore is included.
Microscopic image of protein interactions

NaveniFlex Tissue GR Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a goat and rabbit primary antibody pair. Detection with TEX615 fluorophore is included.
NavenFlex Tissue MR_Atto Colon Beta-Catenin_E-Cadherin interaction

NaveniFlex Tissue MR Atto647N

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with Atto647N fluorophore is included 

NaveniFlex Tissue MR Red

Detect proteins, protein-protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Detection with TEX615 fluorophore is included 
NaveniLink Kit

NaveniLink

Conjugate your own primary antibodies. The NaveniLink kit is for conjugating oligos and primary antibodies for the creation of Navenibodies. The kit is compatible with NaveniFlex Cell, NaveniFlex Tissue and NaveniBright. 
NaveniFlex Cell GM Atto647N

Naveni Control Kit

Control kit to identify positive signals in proximity ligation assays. Use together with NaveniFlex Cell/Tissue/Bright MR.

Naveni TriFlex Cell MR

Detect and quantify total protein A, total protein B, and the interaction AB between the two proteins. The assay is designed to be used with a mouse and rabbit primary antibody pair.
NaveniBright AP in Ovary

NaveniBright AP

Detect proteins, protein – protein interactions, or protein modifications. The assay is designed to be used with a mouse and rabbit primary antibody pair. Chromogenic readout with AP substrate.

NaveniBright HRP

Detect proteins, protein – protein interactions, or protein modifications. The assay is designed to be used with a mouse and a rabbit primary pair. Chromogenic readout with HRP substrate.  

Naveni PD1/PD-L1 AP

Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out
CD8 MHC-I interaction in liver cancer

Naveni CD8/MHC-I Atto647N

Visualize the interaction of CD8/MHC-I in situ. The kit includes primary antibodies specific to CD8 and MHC-I, Navenibodies, and all other reagents needed to run the assay. Fluorescence readout, possible to combine with co-staining.

Naveni PD1/PD-L1 Atto647N

Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Fluorescence readout, possible to combine with co-staining. 

Naveni PD1/PD-L1 HRP

Visualize the interaction of PD1 and PD-L1 in situ. The kit includes primary Navenibodies specific to PD1 and PD-L1, and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out

Naveni pY EGFR

Accurately quantify the level of phosphorylated EGFR in your cells. The in situ kit includes primary Navenibodies specific to phosphorylated EGFR, and all other reagents needed to run the assay.

Naveni pY PD1 AP

Visualize phosphorylated PD1 in situ. The kit includes primary Navenibodies specific to phosphorylated PD1 and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out.

Naveni pY PD1 HRP

Visualize phosphorylated PD1 in situ. The kit includes primary Navenibodies specific to phosphorylated PD1 and all other reagents needed to run the assay. Chromogenic detection and bright-field read-out.
Naveni pTyr HER2

Naveni pY HER2

Phosphorylated HER2, a well-known cancer marker, is now possible to detect in situ. The kit includes primary Navenibodies specific to phosphorylated HER2, and all other reagents needed to run the assay.
pVEGFR2 on VEGF stimulated HUVEC cells

Naveni pY VEGFR2

Visualize phosphorylated VEGFR2 in situ. The kit includes primary Navenibodies specific to phosphorylated VEGFR2and all other reagents needed to run the assay.

Naveni pY MET

Quantify phosphorylated Met in situ. The kit includes primary Navenibodies specific to phosphorylated Met, and all other reagents needed to run the assay.

Naveni pY PDGFR-beta

Detection of phosphorylated PDGFR-beta in situ – now with high signal to noise ratio. The kit includes primary Navenibodies specific to phosphorylated PDGFR-beta, and all other reagents needed to run the assay.